diff --git a/Lib/asyncio/base_subprocess.py b/Lib/asyncio/base_subprocess.py
index 98e72f212aa203..0423bc100b2d93 100644
--- a/Lib/asyncio/base_subprocess.py
+++ b/Lib/asyncio/base_subprocess.py
@@ -22,7 +22,7 @@ def __init__(self, loop, protocol, args, shell,
         self._proc = None
         self._pid = None
         self._returncode = None
-        self._exit_waiters = []
+        self._exit_waiters = set()
         self._pending_calls = collections.deque()
         self._pipes = {}
         self._finished = False
@@ -211,6 +211,14 @@ async def _connect_pipes(self, waiter):
         except (SystemExit, KeyboardInterrupt):
             raise
         except BaseException as exc:
+            # Close any pipes that were already connected before the
+            # error/cancellation to avoid leaking file descriptors.
+            for proto in self._pipes.values():
+                if proto is not None:
+                    proto.pipe.close()
+            for raw_pipe in (proc.stdin, proc.stdout, proc.stderr):
+                if raw_pipe is not None:
+                    raw_pipe.close()
             if waiter is not None and not waiter.cancelled():
                 waiter.set_exception(exc)
         else:
@@ -260,8 +268,12 @@ async def _wait(self):
             return self._returncode
 
         waiter = self._loop.create_future()
-        self._exit_waiters.append(waiter)
-        return await waiter
+        self._exit_waiters.add(waiter)
+        try:
+            return await waiter
+        finally:
+            if self._exit_waiters is not None:
+                self._exit_waiters.discard(waiter)
 
     def _try_finish(self):
         assert not self._finished
diff --git a/Lib/asyncio/unix_events.py b/Lib/asyncio/unix_events.py
index d436512d6c45fc..1a7d534261ed72 100644
--- a/Lib/asyncio/unix_events.py
+++ b/Lib/asyncio/unix_events.py
@@ -213,7 +213,7 @@ async def _make_subprocess_transport(self, protocol, args, shell,
             raise
         except BaseException:
             transp.close()
-            await transp._wait()
+            await tasks.shield(transp._wait())
             raise
 
         return transp
diff --git a/Lib/asyncio/windows_events.py b/Lib/asyncio/windows_events.py
index 8241c10b32d105..efc7c0c158d390 100644
--- a/Lib/asyncio/windows_events.py
+++ b/Lib/asyncio/windows_events.py
@@ -406,7 +406,7 @@ async def _make_subprocess_transport(self, protocol, args, shell,
             raise
         except BaseException:
             transp.close()
-            await transp._wait()
+            await tasks.shield(transp._wait())
             raise
 
         return transp
diff --git a/Lib/test/test_asyncio/test_subprocess.py b/Lib/test/test_asyncio/test_subprocess.py
index ce127e73f50d8a..f9b4fe53acb134 100644
--- a/Lib/test/test_asyncio/test_subprocess.py
+++ b/Lib/test/test_asyncio/test_subprocess.py
@@ -12,7 +12,7 @@
 from asyncio import subprocess
 from test.test_asyncio import utils as test_utils
 from test import support
-from test.support import os_helper, warnings_helper, gc_collect
+from test.support import os_helper, gc_collect
 
 if not support.has_subprocess_support:
     raise unittest.SkipTest("test module requires subprocess")
@@ -1028,7 +1028,6 @@ async def main():
 
         self.loop.run_until_complete(main())
 
-    @warnings_helper.ignore_warnings(category=ResourceWarning)
     def test_subprocess_read_pipe_cancelled(self):
         async def main():
             loop = asyncio.get_running_loop()
@@ -1039,7 +1038,6 @@ async def main():
         asyncio.run(main())
         gc_collect()
 
-    @warnings_helper.ignore_warnings(category=ResourceWarning)
     def test_subprocess_write_pipe_cancelled(self):
         async def main():
             loop = asyncio.get_running_loop()
@@ -1050,7 +1048,6 @@ async def main():
         asyncio.run(main())
         gc_collect()
 
-    @warnings_helper.ignore_warnings(category=ResourceWarning)
     def test_subprocess_read_write_pipe_cancelled(self):
         async def main():
             loop = asyncio.get_running_loop()
diff --git a/Misc/NEWS.d/next/Library/2026-07-21-20-34-05.gh-issue-154389.DlTiii.rst b/Misc/NEWS.d/next/Library/2026-07-21-20-34-05.gh-issue-154389.DlTiii.rst
new file mode 100644
index 00000000000000..eb2e2edc2d720e
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2026-07-21-20-34-05.gh-issue-154389.DlTiii.rst
@@ -0,0 +1,3 @@
+Fix :func:`uuid.uuid1` on OpenBSD:
+it returned a version 4 UUID,
+because ``uuid_create()`` generates random UUIDs on this platform.
diff --git a/configure b/configure
index 71fa0b435d1650..93bc5545e9de6e 100755
--- a/configure
+++ b/configure
@@ -15294,9 +15294,10 @@ then :
 
 fi
 
-# gh-124228: While the libuuid library is available on NetBSD, it supports only UUID version 4.
+# gh-124228: While the libuuid library is available on NetBSD and OpenBSD,
+# it supports only UUID version 4.
 # This restriction inhibits the proper generation of time-based UUIDs.
-if test "$ac_sys_system" = "NetBSD"; then
+if test "$ac_sys_system" = "NetBSD" || test "$ac_sys_system" = "OpenBSD"; then
   have_uuid=missing
   printf "%s\n" "#define HAVE_UUID_H 0" >>confdefs.h
 
diff --git a/configure.ac b/configure.ac
index 5fcf406087cbe5..a9c706f3c23cb1 100644
--- a/configure.ac
+++ b/configure.ac
@@ -4070,9 +4070,10 @@ AS_VAR_IF([ac_cv_have_uuid_generate_time_safe], [yes], [
   AC_DEFINE([HAVE_UUID_GENERATE_TIME_SAFE], [1])
 ])
 
-# gh-124228: While the libuuid library is available on NetBSD, it supports only UUID version 4.
+# gh-124228: While the libuuid library is available on NetBSD and OpenBSD,
+# it supports only UUID version 4.
 # This restriction inhibits the proper generation of time-based UUIDs.
-if test "$ac_sys_system" = "NetBSD"; then
+if test "$ac_sys_system" = "NetBSD" || test "$ac_sys_system" = "OpenBSD"; then
   have_uuid=missing
   AC_DEFINE([HAVE_UUID_H], [0])
 fi