An epigenome-wide association study (EWAS) pipeline profiling DNA methylation (5mC) dynamics across post-mortem Alzheimer's brain regions. Investigates cell-type-specific differential methylation and chromatin accessibility correlations, utilizing OLS with robust standard errors and machine learning biomarker panel classification.
feature-selection dna-methylation biomarker-discovery alzheimers-disease functional-annotation epigenomics robust-regression neurodegeneration ewas pathway-enrichment differential-methylation-analysis neuroepigenetics braak-staging post-mortem-brain illumina-450k differentially-methylated-probes gse59685 machine-learning-biomarkers
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Updated
May 23, 2026 - Python